"Carlo Cudicini has fractured his wrists and injured his pelvis after being involved in a road accident this morning," a club statement said.
"He has been admitted to hospital and undergone scans under the supervision of club medical staff. The club will update supporters on Carlo as soon as there is any further information."
Police were called to a collision between a BMW motorcycle and a Ford Fiesta at 1030 GMT in Walthamstow, close to Tottenham's White Hart Lane stadium.
A Metropolitan Police spokesman said Cudicini's injuries could be "life-changing."
"London ambulance service, Hems (the London air ambulance) and police attended and discovered the 36-year-old male motorcyclist suffering from injuries described by LAS as possibly life changing," a Metropolitan Police spokesman said.
"He has been taken to an east London hospital for further assessment and treatment."
Police confirmed the female driver of the car had not required hospital treatment and there had been no arrests.
Cudicini, who was with Chelsea for 10 years, arrived at Tottenham on a free transfer in January but has spent most of his time at White Hart Lane on the bench after failing to dislodge first-choice keeper Heurelho Gomes.
