In the February draw for the competition's qualification phase, Wales were put into Group B alongside Andorra, Belgium, Bosnia-Herzegovina, Cyprus and Israel.
A trip to Andorra on September 9 marks the start of what looks set to be a tough campaign for a nation seeking a berth at their first major tournament since the 1958 FIFA World Cup.
Chris Coleman's side have only one other scheduled friendly ahead of that visit to the principality, with a testing fixture against the Netherlands set to take place on June 4.
Although more matches may be announced at a later date, manager Coleman recognises the importance of making the most of each game, and he is particularly keen to utilise star asset Gareth Bale.
He said: "We only have a limited number of preparation matches, so it is important that he is with us, but I will monitor the situation.
"He has had a great start at Real Madrid, with plenty of goals and assists. He is adapting well to living in a foreign country and I think he is doing great."
Bale has been in good form for the Spanish giants in his debut season at the Santiago Bernabeu, scoring 10 goals and getting nine assists in his first 17 league appearances.
The world's most expensive player has only featured in two of Wales' last six internationals, mostly down to a problematic spell with injuries at the beginning of the season.
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