Repeat of 2006 final = money back
If Arsene Wenger's side are to stand a chance of qualifying for the semi-final they surely cannot allow Barca to leave North London with any form of advantage to take back to Camp Nou.
FourFourTwo's betting partner Paddy Power make Arsenal 2/1 to win the first leg - a great price considering the Gunners have only been beaten once at home in the Champions League since they moved to Emirates Stadium.
The draw is available at 9/4 and Barca are the 11/8 favourites.
21/10 Arsenal Win 9/4 Draw 11/8 Barcelona Win
If Pep Guardiola's men repeat the feat of the 2006 final and come from behind to beat Arsenal in the first leg Paddy Power will refund all losing first/last goalscorers, correct score and score-cast bets on the match.
It’s not the most exciting of bets but a 0-0 scoreline would be great result for Arsenal, ensuring the Catalans have no precious away goal to take back to Spain.
It appears a massive price at 9/1 but it was the score when both AC Milan and Real Madrid visited North London in recent years, with the Gunners securing victories away from home in the reverse fixture.
Barca have also drawn 0-0 twice on the road in the Champions League already this season so it could be third time lucky for Arsenal.
There’s several big prices to be had on an Arsenal win, but keeping a clean sheet or taking a two-goal lead into the second leg could prove to be decisive.
Arsenal have scored 18 goals in the Champions League this season compared Barcelona’s 12.
Correct Score 9/1 Arsenal 1-0 14/1 Arsenal 2-0 9/1 Arsenal 2-1 35/1 Arsenal 3-0 20/1 Arsenal 3-1 9/1 0-0 11/2 1-1 10/1 2-2 8/1 Barca 1-0 11/1 Barca 2-0 15/2 Barca 2-1 22/1 Barca 3-0 14/1 Barca 3-1
Can anyone stop Lionel Messi? The Flea is 16/5 to score the opening goal and can be backed at 11/1 to score a hat-trick.
Prices start at 80/1 for an Arsenal player to score a treble.
Arsenal captain Cesc Fabregas is fighting to be fit for the match and as the club’s top scorer this season will attract plenty of patriotic support at 15/2 for the opening goal, should he make it.
In the 2006 Champions League final Arsenal took the lead thanks to a Sol Campbell header. He can be backed at 14/1 to score a header in this match again, four years later.