Toivonen double sets up PSV success
Toivonen took his goal tally this season to 10 in the league by knocking in a cross from Carlos Salcido midway through the first half and pouncing again in the 61st minute.
Nordin Amrabat made sure of victory with a last-minute effort against fourth from bottom Nijmegen.
PSV have 51 points from 19 matches, three ahead of Twente Enschede who travel to Groningen on Sunday.
Third-placed Ajax Amsterdam (39) host AZ Alkmaar on Sunday, the same day as Feyenoord (37), in fourth, visit VVV Venlo.