Italy striker Osvaldo, who has been at the centre of a penalty controversy after stealing a spot-kick from Francesco Totti and missing it during their 3-1 defeat at Sampdoria last Sunday, missed training on Friday with a right knee injury, Sky Sport 24 reported.
Midfielder De Rossi is suffering from a knock to his left thigh and is undergoing a special training schedule to get him ready for the clash.
Roma are ninth in Serie A with 34 points from 24 games, 21 points behind champions Juve.
Thank you for reading 5 articles this month* Join now for unlimited access
Enjoy your first month for just £1 / $1 / €1
*Read 5 free articles per month without a subscription
Join now for unlimited access
Try your first month for just £1 / $1 / €1
Get the best features, fun and footballing frolics straight to your inbox every week.
Thank you for signing up to Four Four Two. You will receive a verification email shortly.
There was a problem. Please refresh the page and try again.