The Frenchman has not featured for the Premier League champions since the 1-1 draw at Everton last month after sustaining a calf problem.
Nasri has missed City's last four games, but could feature in Saturday's top-flight clash with struggling Hull City at the Etihad Stadium.
The former Arsenal man has been in fine form for Manuel Pellegrini's side this season and his return is a boost for the manager.
City remain second in the Premier League after holding leaders Chelsea to a 1-1 draw at Stamford Bridge on Saturday.
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