Panathinaikos reclaim top spot in Greece
Greece defender Loukas Vintra set Henk ten Cate's side on their way at the Olympic Stadium with a goal one minute into added time at the end of the first half.
Kostas Katsouranis, with a superb header from 20 yards out after 66 minutes, and Djibril Cisse with two goals in 17 minutes sealed the win which puts Pana two points ahead of Olympiakos, who were 3-0 winners at Levadiakos on Saturday.
AEK Athens' disappointing start to the season continued as Dusan Bajevic's men lost 1-0 to Xanthi, Mauro Poy scoring on 21 minutes.
The result leaves the Yellows in ninth place having lost to Xanthi for the first time in 10 years.
Ergotelis moved third in the table after securing an impressive 4-2 win at Asteras Tripolis.
Latvian Maris Verpakovskis scored twice in the first 22 minutes to give the Cretan club a two-goal lead before Marcelao (45) and Daniel Cesarec (63) levelled the match.
But strikes from Dimitris Orfanos (77) and former Hearts midfielder Deividas Cesnauskis in time added on sealed the points.