Spurs draw United in Carling Cup
In an all-Premier League final eight, Blackburn Rovers will host Chelsea while Portsmouth, who have won just once in the league all season, welcome Martin O'Neil's Aston Villa.
Manchester City's Emmanuel Adebayor and Kolo Toure will get another chance to play former club Arsenal after a controversial league match earlier this season.
The ties will be played in the week commencing November 30.
Blackburn Rovers v Chelsea
Manchester United v Tottenham Hotspur
Portsmouth v Aston Villa
Manchester City v Arsenal