Mourinho labels Wenger a 'specialist in failure'
The Portuguese has stated on a number of occasions that his side are not favourites for the title - a stance Wenger believes shows his rival's "fear to fail".
With just a point separating their respective sides in first and second in the Premier League table, Mourinho hit back at the Frenchman, whose team have not won a trophy since the 2005 FA Cup.
"He is a specialist in failure. I don't fail many times - maybe he is right, maybe I am not used to failure but the reality is he is a specialist," Mourinho said.
"Eight years without silverware, that is a failure. If I do that at Chelsea I don't come back."
Chelsea travel to Manchester City for an FA Cup fifth-round clash on Saturday, with the Londoners having come out on top in their Premier League meeting at the Etihad Stadium earlier this month.
Mourinho insisted that the competition remains a priority for him, before responding to comments from City counterpart Manuel Pellegrini following a number of spats in the media.
"Our priority is always the next match, even in the (League Cup) we lost against Sunderland but it was a priority for us," he added.
"I don't like this talk of records between managers, because it is between teams.
"If I have the record in favour or against (Pellegrini), I don't like both ways. If he doesn't like to speak about me then perfect, I hope he does what he says and doesn't talk about me."