Ajax Ajax head to PSV on Sunday and the Philips Stadion may as well be called the last chance saloon as far as the defending champions' title hopes are concerned.
Vitesse Vitesse Arnhem will face a tough challenge to keep pace with Eredivisie leaders Ajax Amsterdam when they travel to Feyenoord on Friday.
Twente Twente will be out to breathe life into their faltering Eredivisie title hopes and derail leaders Ajax when the two meet this weekend.
PSV Eredivisie leaders PSV take on Go Ahead Eagles on Saturday as they look to strengthen their position heading into the mid-season break.
Twente Twente went top of the Eredivisie on goal difference after Sunday's 5-0 home win over Groningen.
Heerenveen PEC Zwolle moved up to third in the Eredivisie with a 1-0 victory at Willem II on Saturday.
Ajax Frank de Boer believes Ajax's fortuitous 2-1 victory over Go Ahead Eagles last weekend can provide a platform for an upturn in form as they take on Twente on Sunday.
Go Ahead Eagles and NAC Breda will have to survive the relegation play-offs if they are to maintain their Eredivisie status for next season.
Vitesse Title-chashing Vitesse host relegation threatened NEC as Peter Bosz's side seek to extend their undefeated streak to 11 Eredivisie games.
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