Saha to miss Spain friendly
The Everton player had been declared unfit after undergoing medical tests earlier on Monday at the Clairefontaine training ground, he added.
Saha will be replaced by Panathinaikos striker Djibril Cisse who was added to the squad as cover on Sunday.
Saha had been recalled more than three years after he earned the last of his 18 caps in a 1-0 win against Greece in a friendly, in November 2006.
Cisse, 28, last played for France in a 2-0 win against Ecuador in a friendly in May 2008. He has scored nine goals from 37 caps.
Goalkeepers: Cedric Carrasso (Girondins Bordeaux), Hugo Lloris (Olympique Lyon), Steve Mandanda (Olympique Marseille)
Defenders: Aly Cissokho (Olympique Lyon), Patrice Evra (Manchester United), Julien Escude (Sevilla), Rod Fanni (Stade Rennes), Bacary Sagna (Arsenal), Jean-Alain Boumsong (Olympique Lyon), Michael Ciani (Girondins Bordeaux), Adil Rami (Lille)
Midfielders: Lassana Diarra (Real Madrid), Yoann Gourcuff (Girondins Bordeaux), Moussa Sissoko (Toulouse), Jeremy Toulalan (Olympique Lyon), Benoit Cheyrou (Olympique Marseille)
Forwards: Nicolas Anelka (Chelsea), Sidney Govou (Olympique Lyon), Thierry Henry (Barcelona), Florent Malouda (Chelsea), Loic Remy (Nice), Hatem Ben Arfa (Olympique Marseille), Franck Ribery (Bayern Munich), Djibril Cisse (Panathinaikos).