Seven different players got on the score-sheet in Wednesday's preliminary round, second leg at the Mineirao in Belo Horizonte to send home side Cruzeiro through 8-1 on aggregate after Potosi had two players sent off.
Cruzeiro, who also did well to draw the away leg 1-1 in the thin air of Potosi, one of the world's highest cities nearly 4,000 metres above sea level, will meet Velez Sarsfield of Argentina, Chile's Colo Colo and Deportivo Italia of Venezuela in Group Seven.
The Brazilian side's three-man forward line was devastating with Wellington Paulista helping to break the deadlock with a shot that Marquinhos Parana turned into his own net after 29 minutes.
Peru's Juan Aurich qualified with a 2-1 away win over Estudiantes UAG of Mexico in Guadalajara.
They go through 4-1 on aggregate to Group Three to meet compatriots Alianza Lima, title holders Estudiantes de La Plata of Argentina and Bolivia's Bolivar.
Juan Aurich goalkeeper Diego Morales, who made a string of fine saves, told reporters: "The team showed a lot of will and personality."
The team from Asuncion go into Group Four with Lanus of Argentina, Bolivia's Blooming and Universitario of Peru.
