Bordeaux, with just one win in their last six league games, moved up to third with 50 points from 28 games, three points behind leaders Olympique Lyon who host Auxerre on Sunday.
They triumphed thanks to goals by Morocco striker Marouane Chamakh, who opened the scoring from close range after 18 minutes, and defender Henrique, who headed home a cross from fellow Brazilian Wendel just after halftime.
Habib Bamogo had given the visitors hope when he equalised from the penalty spot five minutes after they went behind.
"We needed that win after our bad performance in Toulouse," Bordeaux coach Laurent Blanc told reporters, referring to a 3-0 defeat last week.
"The standings might change again next week but the important thing tonight is that what we have 50 points. It could be better but it's not bad," he added.
Toulouse squandered an opportunity to go second when a late Igor Lolo goal gave Monaco a 3-2 home win earlier on Saturday to hand the visitors their first defeat in 13 Ligue 1 games.
Toulouse are fifth with 49 points from 28 matches.
GIGNAC STRIKES
Ligue 1 top scorer Andre-Pierre Gignac had put Toulouse in front with his 17th goal of the season in the 26th minute before Frederic Nimani levelled six minutes before the break after a free kick by Gignac's cousin Yohan Mollo.
Mauro Cetto put Toulouse back in front with a header in the 67th but two goals in the last 15 minutes from Francois-Joseph Modesto, with a superb scissors kick, and Lolo pushed Monaco up to ninth albeit just four points above the relegation places.
Michel Fernandes Bastos gave Lille a 1-0 victory at Caen, who have not won since late November, to take the northern side into sixth spot on goal difference, four points off the pace.
Stade Rennes recovered from two goals down to snatch a 2-2 draw at Le Mans but slipped one place to seventh on 47 points.
After Lyon host Auxerre on Sunday, second-placed Paris St Germain welcome arch-rivals Olympique Marseille who are three points behind them in fourth.
