Bury's recent form has pulled them six points clear of the relegation zone, but Rochdale head into the derby clash on the back of an impressive 3-0 win at home to Oxford United last weekend.
Scott Hogan's hat-trick took him to 19 goals for the season in all competitions and saw Rochdale close on Scunthorpe United and Chesterfield above them.
The crunch game of the weekend comes at the Kassam Stadium when managerless Oxford United hope to climb above fourth-placed Burton Albion.
Last Saturday's 3-0 loss to Rochdale leaves Oxford five points behind the automatic places in fifth position. Burton, meanwhile, come in to the game buoyed by a first win in five games, the 2-1 win over Accrington Stanley, which included a double strike from top scorer Billy Kee.
Leaders Chesterfield travel to struggling Accrington needing a win after the disappointing goalless draw at home to Portsmouth on Monday night. Accrington need the points for very different reasons after last weekend's 2-1 defeat at Burton left them only four points above the drop zone.
Another goalless draw in midweek that did little to benefit either side was at Rodney Parade where play-off chasing Newport County gained only a point against Fleetwood Town.
Second-placed Scunthorpe entertain Northampton Town in another top-versus-bottom fixture. Russ Wilcox's promotion chasers were stung by a late leveller at Newport last weekend, but will be looking to maintain their 18-match unbeaten run against 23rd-placed Northampton, who have enjoyed a recent resurgence under new boss Chris Wilder.
Other fixtures on Saturday include AFC Wimbledon entertaining in-form York City, Bristol Rovers host John Sheridan's play-off-chasing Plymouth, Portsmouth welcome Cheltenham Town to Fratton Park, while ninth-placed Hartlepool United hope to gain on the play-off places when they visit Wycombe Wanderers.
