Debuchy was carried off on a stretcher just 13 minutes into Arsenal's 3-0 Premier League victory on Sunday after a slight push from Stoke forward Marko Arnautovic sent him crashing into the advertising hoardings behind David Ospina's goal.
And Arsenal boss Arsene Wenger confirmed that Debuchy sustained a dislocated shoulder in the incident and therefore faces another lengthy layoff.
Debuchy spent nearly three months out of action earlier in the season after undergoing ankle surgery.
"It's dislocated so will take a while," said the Frenchman. "He will have to see a specialist."
In more positive news for Wenger, Sunday's game heralded the long-awaited return of Mesut Ozil.
Arsenal's record signing - who had not played since October due to a knee problem - came on as a late substitute at the Emirates Stadium.
"He lacks match fitness but he's fit physically," he added.
"He'll be back fully in two to three weeks."
Arsenal were superb throughout Sunday's game, with Stoke goalkeeper Asmir Begovic making a number of fine saves to keep the score down to 3-0.
"We missed the start of the game at Stoke and paid for it," he added.
"This time we put them on the back foot."
