The Black Stars, who are in Angola without several key experienced players, have had to rely on some of their Under-20 world champions to get past the group stage and knock out host nation Angola in the quarter-finals.
Nigeria, on the other hand, are a little weary after needing a penalty shootout to see off unfancied Zambia in the last eight and then having to travel from Lubango to Luanda for the semi-final at the November 11 stadium.
"There will be (a) need to introduce fresh legs," said Nigeria coach Shaibu Amodu.
"Unlike Ghana we went through 120 minutes and penalties on Monday, spent the whole of Tuesday travelling from Lubango to Luanda and we just have to counter that."
Amodu, however, was confident his squad would be up to the task with a few adjustments from Monday's line-up against Zambia.
"Thanks to my rich bench, certain changes will be made. There are one or two injury concerns, I have to find a suitable replacement for (Onyekachi) Apam who was red-carded on Monday," he said.
"We have to sharpen the attack and stabilise the midfield. These were our greatest areas of worry against Zambia. I have looked at my bench, we have some depth in defence. I need to introduce two or three fresh (pairs of) legs," Amodu added.
"They are a young side, but what I like is that they fight very hard. But they are playing good football, you can see this in their organisation," he told www.fifa.com.
"All I believe is that this side can only get better. That is an advantage of having youngsters playing in a team, with time they gain experience."
"Though they (Nigeria) did not play so well in the game against Zambia, it will be a big mistake to conclude that they will repeat the same performance in the next game against Ghana," the Serb said.
"We have
