Juve were forced to play a game behind closed doors after fans chanted "a black Italian does not exist" at Palermo-born Balotelli in the corresponding fixture last season.
Similar songs have been heard from Juve supporters in the run-up to the game and Italian football federation chief Giancarlo Abete has said the referee and the police will be able to suspend the game for 10 minutes if racist chants occur.
"I will not hesitate to go to the referee and ask for the match to be stopped," the Argentine told reporters.
"Mario is calm, he knows there is no defence against stupidity, he can do nothing about it."
Some of the sting may be taken out of the game if Balotelli, linked in the media with a move to Arsenal, is omitted from Inter's squad like he was for Sunday's 1-0 win over Fiorentina.
Playmaker Wesley Sneijder, key to Mourinho's 4-3-1-2 formation, is struggling to shake off a thigh problem in time.
Champions Inter have barely missed Zlatan Ibrahimovic since his departure to Barcelona earlier this year but Juventus have lacked width and urgency after winger Pavel Nedved's retirement in May.
Third-placed Juve, who slipped eight points behind Inter after Sunday's 2-0 defeat at Cagliari, have seen new Brazilian signings Diego and Felipe Melo fail to shine in midfield.
While the Juventus-Inter game is known as the derby of Italy, with Inter's rivalry with Juve matching if not surpassing that of Milan, another big grudge match takes place on Sunday.
