With a place in the play-off round of Europe's premier club competition up for grabs, the stakes were high across Europe.
And French giants Lyon did enough to win, although only 1-0, against Grasshopper of Switzerland.
Serbian defender Milan Bisevac, who has never scored for Lyon since joining from PSG in 2012, was the unlikely scorer, climbing highest to head home Clement Grenier's free-kick in the 64th minute.
Croatian outfit Dinamo Zagreb left it late but beat Sheriff of Moldova 1-0 at home, with Ante Rukavina coming off the bench to the score the game's only goal with one minute of normal time to play.
Substitute Alexander Kerzhakov – who replaced Andrey Arshavin – scored the winner on 49 minutes, converting Hulk's assist.
Switzerland's FC Basel beat Maccabi Tel Aviv of Israel 1-0 at home, thanks to Valentin Stocker's first-half strike, while Austria Vienna triumphed by the same result, toppling Iceland's FH courtesy of Daniel Royer's strike.
Ukrainian forward Marko Devic scored twice for Metalist – taking his scoring run to seven in five matches – as they beat PAOK of Greece 2-0.
Other results saw Steaua Bucharest of Romania win 2-0 at Georgian club Dinamo Tbilisi, while Kazakhstan's Shakhter Karagandy cruised to a 3-0 win over Albania's Skenderbeu Korce.
