Bilbao batter 10-man Tenerife
The islanders, who have only managed two points on their travels all season, had defender Jose Antonio Culebras sent off after 17 minutes and Bilbao's Fernando Llorente scored from the ensuing penalty.
Gaizka Toquero, Andoni Iraola and Igor Gabilondo sealed the win and moved the Basques onto 36 points from 23 games in seventh.
In other games, Sporting Gijon won 3-1 at Real Zaragoza, Malaga were 2-1 home winners over Espanyol and Osasuna drew 1-1 with Real Valladolid.
Later on Sunday, second-placed Real Madrid host Villarreal looking to cut Barcelona's five-point lead at the top.
The champions crushed Racing Santander 4-0 on Saturday.