The Portuguese cut a frustrated figure as he witnessed his Chelsea side lose ground in the Premier League title race in a 2-1 setback to Sunderland on Saturday, a defeat that saw Mourinho's 77-match unbeaten league run at Stamford Bridge come to an end.
Following that disappointment, Mourinho's post-match press conference had a somewhat sarcastic feel to it, as he offered congratulations to official Mike Dean - who had awarded Sunderland a controversial penalty that was converted by former Chelsea forward Fabio Borini - as well as Mike Riley, the general manager of the Professional Game Match Officials Board, which is responsible for appointing referees to Premier League matches.
Now, the 51-year-old must prepare his charges and focus on what is likely to be Chelsea's best chance of silverware this season.
But victory will not come easy in Tuesday's semi-final first-leg encounter at the Vicente Calderon, against an Atleti side that refuse to relinquish their grasp on top spot in La Liga.
Diego Simeone's men have won eight straight matches in the Spanish top flight in what has been a superb campaign and remain favourites to dethrone reigning champions Barcelona.
Perhaps more impressively was the way that Atleti ensured their first semi-final in Europe's premier competition since 1974, as they overcame Barca 2-1 on aggregate.
The way in which Simeone's side quelled the threat of superstar Lionel Messi over the two legs was a particular highlight.
Indeed, Chelsea's progression to the final four was equally as impressive as Atleti's, as the Stamford Bridge outfit defeated Ligue 1 champions Paris Saint-Germain 2-0 on home soil to overturn a 3-1 first-leg deficit and progress on away goals.
Aside from the question mark over Courtois, Atleti will monitor the fitness of winger Arda Turan, who has recently returned to training following a groin injury.
