Both sides have made indifferent starts to the 2013-14 campaign, sitting on 13 points after as many matches, just three above the relegation zone.
For newly promoted Cardiff, staying up will likely be considered a success, but Stoke may be disappointed with their start under new manager Mark Hughes.
Cardiff lost 3-0 at home to league leaders Arsenal on Saturday but manager Malky Mackay was not upset with their performance.
Of Arsenal's goals, two came in the last five minutes as Cardiff chased a draw, and the result came less than a week after a last-gasp 2-2 draw against champions Manchester United.
Mackay is happy with what he has seen from his players recently but knows that their next two matches – which come against Stoke and Crystal Palace, sides likely to be battling relegation – are crucial.
"It's about being consistent, but also not getting too low. We know what league we're in, and right now it's about having the belief and calmness," Mackay told the club's official website.
"What matters is where we are in May. We have two tough away games coming up, but we've just faced two of the biggest sides in Europe, and we've acquitted ourselves really well."
