Andres Iniesta suffered a calf injury in Barcelona's Copa del Rey victory over Real Sociedad.
Barca confirmed after the first leg of the quarter-final tie that the midfielder had suffered the problem to his left calf and will undergo medical tests on Friday.
The match itself saw Luis Enrique's holders win 1-0, ending their curse at the Anoeta with a first win in nine attempts courtesy of Neymar's first-half penalty, delighting Sergio Busquets.
"The team did themselves proud," Busquests said after the game.
"However, the tie is still to be decided. They [Real Sociead] are a good team."
Final whistle! Barça win 1-0 in Anoeta against Real Sociedad thanks to Neymar's first half penalty January 19, 2017
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