Reggina were in a similarly precarious position when they hosted Milan, who rested key players following their victory over Liverpool to win the 2007 Champions League, and a 2-0 win preserved the tiny club's top-flight status for another year.
Zaragoza's opponents for Saturday's final game of the 2010/11 La Liga season are the much less imposing Levante and Lanzaro is expecting an easier ride given that the Valencia-based club are already safe.
"I played a similar match with Reggina against Milan, who had just become European champions," the Italian defender said in an interview published in Thursday's edition of As newspaper.
"We had to win to avoid the drop and we managed it," added Lanzaro, who joined Zaragoza at the end of the 2009/10 campaign.
"For sure we are going to face a team that could be less focused than us, who are playing for our lives, because they have already secured their objective.
"I don't think they will have the same aggression and concentration as usual."
Deportivo host Valencia, who are assured of third and an automatic berth in next season's Champions League, Real Sociedad are at home to Getafe, Osasuna host fourth-placed Villarreal and Mallorca are at home to Atletico Madrid.
"We are going for the three points and try to end the season as well as possible because it's not the same getting a direct spot (in the Europa League) as having to qualify," Atletico midfielder Koke told a news conference on Wednesday.
"It's always nice to have a longer vacation," the 19-year-old added.
"Cristiano has scored nearly 40 goals so we're all very happy for him," Real's Argentina striker Gonzalo Higuain said at a media event on Tuesday. "He deserves the Golden Boot and we hope he wins it."
