Edinson Cavani broke the deadlock midway through the first half with a glancing near-post header from Lucas Moura's corner, the Uruguay international's 13th goal of the season.
PSG went in at the break two goals to the good after Cavani was felled in the area and Zlatan Ibrahimovic impudently chipped the resulting penalty home.
The result leaves PSG four points clear of Lille at the top of Ligue 1, and Laurent Blanc's side are now just one game away from equalling their longest ever unbeaten run in the league.
Laurent Blanc made two changes from the 2-1 UEFA Champions League win over Olympiacos in midweek, Javier Pastore making his first start since November 9 in place of Ezequiel Lavezzi, while Clement Grenier replaced Steed Malbranque in Lyon’s sole alteration.
Alexandre Lacazette rattled the crossbar for the visitors, but PSG responded with Pastore forcing Bakary Kone into a brave block at the other end.
The hosts did break the deadlock soon later though, Cavani glancing Lucas’ corner through a crowded penalty area and past Vercoutre.
Ibrahimovic duly converted with a composed chip into the top corner, as PSG tightened their grip on the game.
Blanc's men nearly had a fourth five minutes later when Cavani headed Ibrahimovic's cross just over the bar.
Verratti, dismissed in PSG's midweek win over Olympiacos, responded brilliantly, pulling the strings for the hosts with great effect.
