Paris Saint-Germain broke the Ligue 1 points record thanks to a 4-0 win over Gazelec Ajaccio on Saturday, while Lyon's stunning 6-1 victory against Monaco all but assured them of a place in the Champions League group stage.
Edinson Cavani scored a hat-trick as PSG dominated lowly Gazelec, with Zlatan Ibrahimovic adding gloss to the result in stoppage time - his 35th goal of the season.
In Lyon, the hosts had already opened up a 2-0 lead by the time Monaco's Lacina Traore was sent off for a second bookable offence in the 23rd minute, and goals from Mapou Yanga-Mbiwa and a second from Alexandre Lacazette doubled the advantage.
Lyon's victory sends them three points clear of Monaco, who have a far inferior goal difference.
The visitors had both Kevin Malcuit and Franck Tabanou sent off early in the second half, with Valere Germain striking twice in the last four minutes to strengthen Nice's grip on a Europa League berth.
Sixth-placed Lille aided Nice's cause by failing to overcome Guingamp in a goalless draw.
The bottom end of the table is poised nicely for next weekend's final round of fixtures, with Toulouse, Gazelec and Reims - separated by one point - all looking to avoid the two remaining relegation spots.
