Low named a strong side for the clash at Borussia Park but saw Cameroon take the lead through Samuel Eto'o shortly after the hour mark.
Thomas Muller and Andre Schurrle swiftly responded to put Germany in front, but Eric Maxim Choupo-Moting fired an equaliser late on to leave Low and his men with work to do ahead of a meeting with Armenia on Friday - their final friendly before the FIFA World Cup.
"With us, one has noticed that the freshness is missing," he said.
"Our passing game was not good and we made many, many mistakes. If we had taken the lead, it would have helped the team.
"It pervades through the last few years that we need many opportunities (to score)."
Mesut Ozil was among those to start as Low recalled a number of his star names after fielding a youthful team against Poland last month.
"Mesut Ozil has not had his best day," he stated.
"He needs two more weeks, then we'll see a strong Mesut at the World Cup."
