"This is a match with high risks, although the risks are reduced by the fact that there will be very few visiting supporters," Marseille police chief Jean-Luc Marx told reporters.
Marseille fan Santos Mirasierra was sentenced to three-and-a-half years in prison for assaulting police officers during his side's Champions League match at Atletico Madrid two months ago.
The case has been a source of rising tension ahead of Atletico's trip to Marseille for their final Group D match.
"The risk comes for excessive passion or violent attempts that could be directed towards the visiting team or the country they represent," Marx added.
"We hope to close the Marseille chapter once and for all on Tuesday," Aguirre told a news conference in Madrid.
"I am sure there will be the highest possible level of security," he said, adding that the squad had been advised to travel to France only on the day of the match as a precaution.
"My team and I would have gone the day before but if UEFA recommends going on the day we cannot do anything else. We are travelling to a civilised country. My players are relaxed."
Atletico's French striker Florent Sinama-Pongolle said he was expecting a "warm but nice" reception in Marseille.
"I am sure the security personnel will do a good job and we hope that nothing happens," he said. "I hope that people will come to watch a football match and nothing more."
UEFA said failures in the home side's organisation led to the confrontations and initially ordered Atletico to play their following two European games at least 300 km from Madrid.
