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The Denmark international hobbled off after just 30 minutes of the 2-1 defeat against Newcastle United on Saturday following an innocuous challenge on Loic Remy.
And, after undergoing tests to determine the extent of the problem on Monday, the centre-back has now been told that he has suffered cruciate ligament damage that will require surgery.
A statement from the club on their official website read: "Following clinical examination and the results of an MRI scan, the club can confirm that Jores Okore sustained a ruptured anterior cruciate ligament injury in his right knee in the game against Newcastle on Saturday.
Article continues below"Jores will undergo surgery in due course and he could be sidelined for a period of up to nine months."
Okore, 21, arrived on a four-year deal from Nordsjaelland in June for a fee believed to be in the region of £4million and won high praise for his early Premier League performances.
