Chris Eaton (pictured) said that, as part of its response, FIFA wanted to provide witness protection for players who came forward when they were approached by match-fixers and would consider rehabilitation for those corrupted at a young age.
It would also set up a hotline open to anyone to provide information on suspicious behaviour.
"We want to manipulate the manipulators and intimidate the intimidators; they have to realise that we are serious and FIFA is going to protect its people, its sport against these people who have no conscience at all," he said.
"Infiltration is a strong word but my assessment is that organised criminality has infiltrated at several levels of football for the precise purpose of making money from the enormous amount of gambling income which is now being generated."
Buying clubs was a way for organised groups to control the results of matches, warned Eaton, who worked at Interpol for more than 12 years before joining FIFA.
"We're seeing a trend for the purchase of low-level clubs and the movement of players and the trafficking of players," he said, adding that this happened mainly in "less wealthy" countries.
"There is a significant trend in the trafficking of players, moving them into other leagues with a mentor, normally a player who comes from the same country or region, has a great deal of respect, is more than likely corrupted, who is able to influence these players.
"We're seeing referees' development schools and player development schools, some of which are clearly a front for criminals. They are investing long-term in the compromise of these players.
"They [development camps] are often endorsed by a federation and perhaps the federation doesn't realise who is behind the operation."
Match-fixing, usually by illegal gambling rings, has become a major problem for football in the last few years.
In one recent case in Finland, Wilson Raj Perumal, a Singaporean national, was jailed for two years while nine players - seven Zambians and two Georgians - were given suspended sentences for trying to fix matches.
Perumal paid players up to 20,000 euros per match and received up to 50,000 euros, in addition to some of the betting profits, each time the results of the Rovaniemi team were fixed.
Eaton said the approaches to players or referees would often begin with a gift.
"They'll go to a player and they'll say: 'You played a great game today, I made some money off you, here's 1,000 euros'.
"The next time he plays, the same person will give him another 1,000 euros - for some of these players, we're talking about third or fourth division, it's more than they would make for the game.
"The third time they say: 'I can give you 10,000 euros if you don't score a goal today, or if you let a goal in today'.
"They wait outside the changing-rooms, they know the players, they know where the players live, drink, they'll have a mentor.
"This is what Perumal did to several African players in Finland: he gave them some money as gifts, then asked them to do something for him when they were ingratiated and compromised by him."
Eaton added that not all attempts to fix games were successful.
"These are athletes, they get involved in the game and they forget about their agreement. They become enthused in the match and it doesn't go the way it was supposed to go and they're punished."
"We have examples of players being severely bashed, [and] referees."
Earlier this year, FIFA set up a task force with Interpol, promising to donate 20 million euros to the fight again
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