Penarol, in Uruguay's Clausura championship, and Cerro Porteno, in the Paraguayan Apertura, maintained perfect records with 15 points after five matches.
PERU
Alianza Lima continued to celebrate with their fans the brilliant 4-1 win over Libertadores Cup holders Estudiantes of Argentina last week, beating Alianza Atletico 3-0 at home to notch their first victory after two matches in the league.
Alianza scored their three goals in the final quarter of an hour, two by Paraguayan striker Roberto "Buffalo" Ovelar.
Winger Wilmer Aguirre, their hat-trick hero on Thursday, said he was happy to be back in the fans' favour after coming on as a substitute and injecting more urgency to the Alianza attack.
"Before the fans would criticise me and now they applaud me, I have to thank them for this gesture," Aguirre told reporters. "This is just the beginning, there's a long way to go and we must keep playing the same way."
CNI, whose Argentine defender Hector Gaitan is recovering from a mugging in a restaurant last week, beat Sport Boys 3-1 at home in the Amazonian city of Iquitos.
The visitors had two players sent off in the opening 37 minutes, Michel Guevara and Hector Vasquez, but still managed a 45th minute equaliser by striker Vitor Rossel after midfielder Marcos Delgado had put the home side ahead in the third minute.
Striker Andy Pando and midfielder Carlos Barrena scored second half goals for CNI, who had Juan Vergara sent off 20 minutes from the end.
Champions Universitario went down to their second defeat, 2-1 at Juan Aurich.
COLOMBIA
Three players were sent off in Atletico Nacional's 1-0 home victory over Atletico Junior, two from the winning side.
Nacional defender Andres Orozco was shown the red card after 45 minutes for elbowing an opponent and midfielder Jose Amaya was sent off at the end. Junior midfielder Frank Pacheco was dismissed in the 56th.
Giovanni Moreno scored the only goal in the 35th minute to end Junior's unbeaten run since the championship started.
Real Cartagena, with 13 points from five matches, opened a three-point lead with a 1-0 win over America. Champions Independiente Medellin are joint second after a second consecutive win, 2-1 at Cortulua.
CHILE
Holders Colo Colo came from two goals down in the last half hour, with two from Argentine substitute Ezequiel Miralles, to beat Audax Italiano 3-2 away.
The winner five minutes from time was an own goal by Audax defender Carlos Garrido.
Ten-man Union Espanola, whose defender Miguel Angel Aceval was sent off after half an hour, handed Universidad Catolica their third defeat in a row, winning 2-1 with a 90th-minute effort from substitute Roberto Ordones.
Union Espanola went top with 14 points from six matches, a point ahead of Universidad de Chile. Colo Colo are fifth with 10 points.
