Chile can book their place in the Copa America quarter-finals with a victory over Mexico on Monday.
The tournament hosts kicked off their campaign with a 2-0 win over Ecuador, and a subsequent goalless draw between Mexico and Bolivia handed them the chance to wrap up their progression with a game to spare.
Miguel Herrera insisted last week that the squad he had brought to Chile was not a 'B' team, with key figures such as Javier Hernandez and Giovani dos Santos rested ahead of the Gold Cup.
Herrera may now view the clash with Chile as a must-not-lose encounter and says he is well aware of the threat posed by Jorge Sampaoli's side.
"We will work for what it takes to play Chile," he said. "It is a team with skilled players, especially Alexis Sanchez - he is a very dangerous guy.
"It will be a very difficult match and we will concentrate very hard in order to win the ball and keep it.
"The important thing is to stay strong."
The 36-year-old lasted just over an hour in his side's opener before being replaced by Javier Aquino.
