Nigel Clough's side face one of the biggest games in their recent history next Sunday when they head to the English national stadium for their FA Cup semi-final meeting with Hull City.
Up for grabs is a first FA Cup final appearance for the club since 1936, but first they must contend with a derby clash against their near-neighbours in league action.
Rotherham's hopes of promotion are far more realistic, though, following a magnificent 16-game unbeaten run that has put them on the brink of sealing a spot in the Championship.
A 3-1 loss to Coventry City on New Year's Day marked the last time that Steve Evans' men suffered defeat in the league, and they are now just six points adrift of Brentford, who occupy the second automatic promotion place.
John Gregory's team have lost all of their last five encounters, leaving them just three points above the bottom four.
But the former Aston Villa and Derby County boss insists that his side's survival hopes remain in their hands.
"It's the first time I've had to look over our shoulders since I've been here," Gregory said after Saturday's 2-1 home loss to Crewe Alexandra.
"Some of the results in the bottom half were not good for us today.
"But it's in our own hands and other clubs around us don't have the luxury of the games in hand."
