Gordon Igesund's side fell to their third defeat in their last six matches on Wednesday, suffering a 2-0 loss to the Super Eagles in the Nelson Mandela Challenge.
The visitors come into the game unbeaten in their last three outings, and off the back of a morale-boosting 2-1 win over Morocco.
South Africa are likely to name a much-changed side from the one beaten in Durban and Igesund is confident that they can learn from their mistakes.
"We can only improve from this performance," he said following the Nigeria defeat. "When you look at their play, you can tell they have been playing good oppositions.
"They (Nigeria) looked sharper but we were also a bit rusty, having last played against Ethiopia in June.
"We learnt a lot from this outing and we know where to rectify.
"It's a big occasion for us but at the end of the day we need to go out there and win the game."
Igesund's side have only lost once in six matches and will be keen to return to winning ways ahead of their final World Cup qualifying game.
