Hajime Moriyasu's men are aiming to secure a third consecutive Japanese top-flight crown but have slipped up in recent weeks.
A goalless draw with Albirex Niigata was followed by a 3-0 home defeat to Kashima Antlers on Saturday, leaving Sanfrecce fourth, albeit only a point behind the top three.
Leaders Kashima host a Shimizu S-Pulse team who are enjoying a welcome resurgence following their dismal start to the campaign.
Ryo Adachi's men were knocked off top spot at the weekend courtesy of a 2-2 draw with Cerezo Osaka, but have lost just once this season.
Tokushima have yet to claim a point and scored only their second goal in nine matches in Saturday's 2-1 loss to Albirex.
A trip to Ventforet Kofu promises to be no easy task for the league's bottom club, with the hosts having claimed two straight wins to pull away from trouble.
Last year's runners-up Yokohama F Marinos are just four points above the relegation zone ahead of their trip to Urawa Red Diamonds.
Elsewhere, Cerezo host Omiya Ardija and Vegalta Sendai meet Kawasaki Frontale.
