While Glory head coach Kenny Lowe has played down his team's poor form, Saturday's match at Allianz Stadium in Sydney will see two of the A-League's struggling sides clash for a crucial three points.
Perth have not won in four games, with only Newcastle Jets on a worse run of form, but in a boost for the Glory, they will face the most embattled club in the A-League in Sydney after the Sky Blues' fans staged a mass protest last week.
Marinkovic, Sernas and Griffiths all arrived in the January transfer window and while they have not had long to get settled in Perth's purple shirts, Lowe needs a boost from the trio, as well as Glory's other mid-season recruit William Gallas.
"There are nine games left," Lowe said on Tuesday.
"We're three points off fourth, aren't we? What's all the hassle? Chill out, we'll be all right."
Sydney's fans held up banners during the game calling for the sackings of head coach Frank Farina, CEO Tony Pignata and chairman Scott Barlow.
When one supporter was ejected from Allianz Stadium for refusing to give up one of the banners, the rest of Sydney's active supporter group The Cove left the ground, before continuing their protest outside the venue.
The loss to Adelaide was Sydney's sixth in eight matches and their third in a row at home.
The Wanderers and Melbourne Victory completed their round 19 match in December as the latter have an AFC Asian Champions League play-off against Thailand's Muangthong United to play this weekend.
