Previews: Arsenal defence down to bare bones
Arsenal's defensive problems are set to continue for their FA Cup semi-final against Chelsea at Wembley on Saturday with fullbacks Bacary Sagna (virus) and Kieran Gibbs (groin) struggling to be fit.
Goalkeeper Manuel Almunia is still unavailable so Pole Lukasz Fabianski will continue in goal.
Chelsea captain John Terry should return to the side after missing the midweek Champions League aggregate victory over Liverpool through suspension.
Everton manager David Moyes has an injury doubt over striker Louis Saha who has a stomach virus ahead of their FA Cup semi-final against Manchester United on Sunday.
Brazilian on-loan striker Jo is cup-tied but defender Joseph Yobo and striker James Vaughan have recovered and are in the squad.
Manchester United manager Alex Ferguson has said he will make changes to his team after the midweek Champions League victory over Porto.
"The game was played at such a high tempo that it would be impossible to play the same team again (on Sunday). I will freshen things up," he told the club's website.
Aston Villa, who still have slim hopes of qualifying for the Champions League, could be without England forward Gabriel Agbonlahor who has a hamstring injury ahead of their match at home to West Ham United on Saturday.
Defensive duo Carlos Cuellar and Wilfred Bouma are also struggling to be fit along with midfielder Steve Sidwell.
Relegation threatened Newcastle United are boosted by the return of Australian striker Mark Viduka for Sunday's trip to Tottenham.
The 33-year-old has not played since suffering an Achilles injury in the 1-0 defeat by Bolton on March 1.
Tottenham welcome back Honduran midfielder Wilson Palacios who returns after suspension. He could take the place of Jermaine Jenas who is a doubt to face his former club because of a hamstring injury.
Blackburn have wingers El Hadji Diouf and Morten Gamst Pedersen available for the relegation battle at Stoke City after the pair overcame a throat infection and calf injury respectively.
However, strikers Roque Santa Cruz (knee) and Jason Roberts (foot) and midfielders Brett Emerton and Steven Reid (both knee) are all unavailable.
Middlesbrough goalkeeper Brad Jones is set to start against Fulham on Saturday despite dislocating his finger last week but Emanuel Pogatetz (knee) and Gary O'Neil (suspended) are out.