Antonio Conte's men are seeking their third consecutive Serie A title but, despite a superb start to the campaign, they sit just third in the table after the first 11 games.
Napoli are above Juventus on goal difference, with both teams three points adrift of unbeaten league leaders Roma, who welcome struggling Sassuolo earlier on Sunday.
Attacking midfielder Arturo Vidal has also been in fine form, scoring five times in Serie A, while the recent performances of striker Fernando Llorente - a scorer in the 2-2 UEFA Champions League draw with Real Madrid in midweek - should also come as a boost to Conte.
Juventus and Napoli have combined for 47 league goals so far this season, and visiting manager Rafael Benitez is anticipating an exciting game.
"I think it's going to be a fantastic game between two teams that are doing very well," Benitez said.
"Juventus are the defending champions and I believe they will have a slight advantage as they have one more day to prepare for the game than we do."
