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José da Rocha Fonte Both Southampton and Borussia Dortmund have work left to do to ensure their place in the UEFA Europa League group stages.
Twenty-nine UEFA Europa League ties were settled on Thursday, completing the list of clubs competing in the play-offs and West Ham will not.
Spots in the UEFA Europa League final qualifying round are up for grabs, with 29 ties set to be decided on Thursday.
Southampton won comfortably, West Ham saw red in another struggle and Sampdoria were humbled in the Europa League qualifiers.
Borussia Dortmund ran riot with a 7-2 win over Odd in the UEFA Europa League, while AZ scored twice late on to beat Astra.
AC Milan, Marseille and Everton learned their fate in Friday's Europa League play-off draw. Here is the draw in full.
Borussia Dortmund claimed a stunning comeback win as Jay Rodriguez's first Southampton goal in over a year salvaged a draw with Midtjylland.
Saint-Étienne Supercopa de Espana winners Athletic Bilbao return to UEFA Europa League action in their play-off first leg clash with Zilina.
