Alex, who joined PSG from Premier League Chelsea during the January transfer window, missed last weekend's 3-1 defeat of Evian Thonon Gaillard with a calf injury.
"We know it's always a tough game, playing Nice at their Stade du Ray, but we're not going to let go of anything," said striker Kevin Gameiro.
Gourcuff, who has made only seven Ligue 1 appearances this season and has not featured for France in almost a year, played in Lyon's 3-1 extra-time French Cup quarter-final win over Girondins Bordeaux on Wednesday but was replaced midway through the second half having looked far from his brilliant best.
"He is very close [to playing more regularly]," coach Remi Garde told French radio RMC this week.
"He had a minor knee injury [earlier this season] but he is getting close to the level that will allow him to play more," said Garde. "It's a team sport, so we need everybody."
