The trio were overlooked by Diego Maradona for the recent World Cup finals in South Africa, where Argentina crashed out in a 4-0 quarter-final defeat by Germany.
"Gabriel has shown me can bring the ball out well from defence, he has good left foot with good touch," Sergio Batista, Maradona's successor, said of Barcelona centre-back Milito.
"Javier is a player of great experience who moves into attack with conviction," Batista told a news conference on Monday speaking of the return at right back of Zanetti, who has an Argentine record 136 caps.
"Cambiasso is a coach on the pitch," he added of the midfielder, a key player in the Inter Milan side that won the European Champions League in May.
"The idea is to maintain a playing identity. We have players capable of that," said Batista, a commanding central midfielder in the Argentine side led to the world title by Maradona in 1986.
Batista has, however, retained Maradona's attacking trident of Lionel Messi, Gonzalo Higuain and Carlos Tevez.
"Mache will have to be beyond the halfway line to play more," Batista said.
Mascherano will be flanked by Cambiasso to his left and on the right by Ever Banega, who was also overlooked for the World Cup but returned for Batista's first match in charge, a 1-0 friendly win over Ireland in Dublin last month.
"It's six years of work against six days," he said.
