Nigel Pearson's Championship leaders have enjoyed a magnificent campaign and sit 16 points ahead of third-placed QPR with seven games remaining.
The Midlands outfit, who have endured a 10-year absence from the top flight, were held to a 2-2 draw by Wigan Athletic in midweek but will seal a return to the Premier League if they avenge December's defeat at Sheffield Wednesday, QPR lose to Bournemouth and Derby County fail to beat Middlesbrough in Saturday's games.
Meanwhile, second-placed Burnley will look to boost their own promotion hopes by beating Watford, but travel to Vicarage Road without their two premier striking threats.
Sam Vokes ruptured the anterior cruciate ligament in his left knee during last weekend's 2-0 defeat to Leicester and joins Danny Ings on the sidelines.
"As ever, our team mentality remains focused and this represents another opportunity for someone to come and make a continued contribution in the closing weeks of the season," Dyche told his club's official website.
QPR's trip to Bournemouth presents a considerable test for the London side, whose manager Harry Redknapp returns to face a club he managed between 1983 and 1992.
