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The Ghanaian, who spent last season on loan at Real Madrid, has struggled to hold down a place in Jose Mourinho's side in England, making just nine appearances in all competitions this season.
Nemanja Matic's arrival at Stamford Bridge pushed him further down the pecking order in midfield, making a move to Italy look increasingly likely.
"To show Michael respect is to not stop him going," he said. "We would have been happy had he stayed because he is fantastic player for the team, but he's given everything for the club and a great chance arrived for his future.
"I know he can continue to play at a high level and I wish him success and happiness in Italy and at the World Cup in Brazil."
