With Wayne Rooney suspended and Jermain Defoe and Andy Carroll injured, Bent is likely to be the first striker on manager Fabio Capello's teamsheet for the match at Wembley as the Italian looks to keep his side top of Group G qualifying.
"It's a massive game for me because I want to play for England as many times as I can and try and establish myself as the number nine," Bent told a news conference on Wednesday.
"It will be quite hard for England to leave him out because he's a goal-a-game man," said winger Downing.
"He's always in the right position to score goals - and those people are priceless."
The 27-year-old Bent has already scored against Switzerland in this qualifying campaign, grabbing the third in September's 3-1 win in Basel before goals in February's friendly against Denmark and the March qualifier against Wales made it three goals in his last three internationals.
"It's worked out really, really well," he said. "Fabio keeps picking me so as long as he keeps doing that I must be doing something right," said Bent.
With attention on Switzerland for different reasons of late as the crisis at football's governing body FIFA has been unfolding at its Zurich headquarters, Euro 2012 matches have not been getting as much media attention as they might usually.
Switzerland, third with four points, have their own forward options to consider following experienced strikers Alexander Frei and Marco Streller's recent international retirement.
Coach Ottmar Hitzfeld may thrust 22-year-old Innocent Emeghara and 20-year-old Admir Mehmedi into action, telling uefa.com: "We are lacking strikers aged around 25 or 26 so I had to call up really young ones to fill the gap".
Bulgaria (four points) and Wales (zero) are the other teams in the qualifying group for next year's tournament in Poland and Ukraine.
