Manuel Pellegrini's high-fliers steamrollered Norwich in the reverse fixture at the Etihad Stadium and will be seeking a quick response following Monday's 1-0 loss to title rivals Chelsea.
Defeat at the hands of Chelsea ended a 20-match unbeaten run for City, who had scored in their previous 61 home league games.
Norwich are embroiled in a relegation battle and go into this weekend's matches just two points clear of the bottom three in 15th.
Chris Hughton's side surrendered a lead when losing 2-1 to fellow strugglers Cardiff City last time out.
Yet Hughton is remaining positive as Norwich prepare to welcome one of the league's strongest teams.
"Manchester City can score goals at will," he said. "But it's a really good challenge for us. We have to put everything together and look forward to it."
Fellow defender Michael Turner (hamstring) and midfielder Jonny Howson (back) are nearing returns but will be unavailable on Saturday.
