Liverpool manager Roy Hodgson said he would replace all 11 players from Wednesday night's humiliating Carling Cup defeat to League Two Northampton Town when they play Sunderland on Saturday.
A largely second-string Liverpool team went out of the competition 4-2 on penalties after a 2-2 draw at Anfield.
"None of the players who are playing on Saturday played on Wednesday night," Hodgson said on the club website.
"We had a very bad result on Wednesday night but it should not affect the 11 players who are going to start the game on Saturday because they weren't part of the game."
"Kuyt is the only one we have a slight reservation about, but we'll see if he makes it," Hodgson added.
Chelsea look certain to be without both Yossi Benayoun and Salomon Kalou for Saturday's match.
"I don't think Kalou will be available for the Manchester game, also Benayoun," manager Carlo Ancelotti said on the club website.
"It is a muscle problem so we need more time for him to rest."
"Owen Hargreaves has come back (to) training, he trained yesterday with the first team," Ferguson said on the club website.
"He looked very good. I was surprised actually how good he was looking."
Arsenal will be without captain Cesc Fabregas and defender Thomas Vermaelen for Saturday's match against West Bromwich Albion but midfielder Abou Diaby could return to the side.
"The only player who could come back is Diaby," manager Arsene Wenger said on the club website.
"He will have a test on Friday morning and we will see from there.
"Thomas Vermaelen will be out for the next two games. Cesc Fabregas is out 100 per cent for the next two games. We have a small hope he could be back against Chelsea."
