Guatemala have never qualified for the World Cup while Canada have made just one appearance, back in 1986, and they start their respective qualification campaigns for the 2018 tournament in June.
Benito Floro's Canada face the British Virgin Islands or Dominica in the second round of qualifying, while Guatemala begin their bid for a place at the finals in Russia against either Bahamas or Bermuda.
On paper it is Guatemala who head into this game at Lockhart Stadium in Fort Lauderdale, Florida, as favourites to overcome Canada and go further at the Gold Cup.
"We have two priorities for this camp," Floro said. "The first is to work hard on tactical concepts like pressing, combined attacks, defence, and our offensive and defensive set pieces.
"At the same time, we need the psychological attitudes to get results. We need to have a good mentality."
And Floro feels testing themselves against sides like Guatemala and Puerto Rico - who they face three days later - will prove vital in Canada's preparations for competitive matches.
"Every day we are together is very important to us because it is the best way we have to practice our game situations," he added.
"Speaking about this camp, this is very important because it is the last one before official games so we need to use it to practice several things."
