Atletico Madrid, who beat Athletic Bilbao 3-0 to win the Europa League final on Wednesday, are eying a bigger prize for next season as they battle Malaga and Levante for Spain's fourth and final Champions League place.
A clutch of teams could make it into Europe's second-tier club competition and five teams are scrabbling to avoid joining already relegated Racing Santander in the second division.
A victory would give Jose Mourinho's men a new La Liga record 100 points, beating by one the mark set by Barcelona in 2010, and would add to their league goal-scoring record which sits at 117 with one left to play.
Deposed champions Barca play the last league game of Pep Guardiola's tenure at Real Betis on Saturday, when Lionel Messi has the chance to build on his La Liga record tally of 50 goals.
The Qatar-owned club are in pole position to secure Spain's last remaining ticket into Europe's elite club competition, and some pay back on the millions invested in the club since it was bought two years ago.
"Possibly, this week is one of the most important in the club's history," Malaga's Portuguese midfielder Duda told reporters.
"It will be an emotional game, but with different emotions to those of other years where we have been playing to avoid relegation."
Atletico are two points behind them in fifth, and need to raise themselves for one final effort away at relegation-threatened Villarreal. Seventh-placed Levante's slender options require a victory over Bilbao and other results to go their way.
