Since losing back-to-back matches, Queretaro are unbeaten in three to sit sixth in the Liga MX standings from 10 outings, eight points adrift of league-leading America.
The 2008 champions produced another impressive result on Friday, drawing 1-1 at home to fourth-placed Toluca.
"I have a great team, very well run, we are playing very attractive football and I hope that we get a good result," said the 49-year-old.
"We will improve the offensive end. Hopefully we have a good game that allows us to add [to our points tally]."
Queretaro will face an Atlas team still stinging from Saturday's loss to second-placed Monterrey, who scored two first-half goals to record a 2-1 win.
Leon have collected three points from a possible 15 to languish in 16th spot, just three points above basement club Morelia.
"Football is very complicated. Leon in the last tournament was wrong and then changed everything and was the champion," said the Brazilian.
"Leon we know are not a good time, but has very good team. We have to be very careful because they have very fast players.
"We know that and how difficult it will be the game. We have to get quiet, but it's eleven against eleven. We must seize opportunities and be sure to claim three points."
Full-back Miguel Layun was an unlikely hero for America last time out, scoring four goals as Antonio Mohamed's men trounced Santos Laguna 4-1.
Tijuana go head-to-head with Cruz Azul, while Toluca face Guadalajara on Thursday.
