Leaders Paris Saint-Germain will be without defender Maxwell and midfielder Clement Chantome because of thigh injuries, as well as holding midfielder Mohamed Sissoko and winger Nene through suspensions when they travel to Caen on Saturday.
Coach Carlo Ancelotti is likely to field Blaise Matuidi to make up for Sissoko's absence and Christophe Jallet in place of Nene, while Siaka Tiene will replace Maxwell.
"We have no pressure. We never said we had to play in the Champions League next season while Lyon must secure a place [in the Champions League]," Batlles told Saint-Etienne's website.
"Let's not forget they beat Lyon 2-0 [two weeks ago]," Girard told a news conference.
"And they're very physical, which means we'll have to be very focused on set pieces."
Valenciennes holding midfielder Carlos Sanchez has been suspended for nine matches for a dangerous tackle on Saint-Etienne's Fabien Lemoine, who will be sidelined for six weeks with an ankle injury, the French league said.
