In a rematch of one of the Western Conference's semi-finals last year, Galaxy will be looking for revenge against their hosts, who have one win and a draw so far in 2014.
Real defeated Galaxy 2-1 on aggregate in their two-legged semi-final thanks to Christopher Schuler's extra-time strike in Utah.
Due to the vagaries of the MLS draw, Saturday's game will be the fourth consecutive match between the two teams with Galaxy having opened their domestic campaign with a 1-0 loss to Real in LA.
Joao Plata scored the winner for Real in that game and with two goals in as many games, the Ecuadorian forward will have to be watched by Galaxy's defence at Rio Tinto Stadium.
Plata scored Real's second goal in their scintillating 3-3 draw at San Jose Earthquakes last week.
Real's goalkeeper Nick Rimando injured his back in that match but played out the 90 minutes and the 34-year-old has claimed he will be ready to take on LA.
"Never had a feeling like that with my back," Rimando said at training this week.
"With some treatment, the back loosened up. No problems at all. I feel 100 per cent."
"Rob isn't one of these (target forwards) that you can just smack the ball up to him and he flicks (it forward), he holds the ball up and gets involved in the play," Keane said.
"It gave myself and Landon (Donovan) a lot of joy just behind him."
Chivas beat Chicago Fire in their opening match before drawing with the West's leaders Vancouver Whitecaps last week, while Dallas trumped Montreal Impact before drawing with reigning champions Sporting Kansas City.
